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2-aminoindane is an amphetamine (AMPH) analog with a rigid conformation due to a bridge between the a-carbon and the aromatic ring (8). In the 1990s, Nichols et al. synthesized cyclic analogs of 3,4-methylenedioxyamphetamine (MDA), MDMA, 3-Methoxy-4-methylamphetamine (MMA), and p-iodoamphetamine (PIA) containing the 2-AI compound. Their procedures for synthesizing aminoindanes were well described (9-13). NPSs synthesized from the substances listed above are MDAI, MDMAI, MMAI, and 5-IAI (Table 1); all of these are psychoactive and their presence on the market has been confirmed in confiscated samples of “legal highs” (14). The EU Early Warning System5 and the United Nations Office on Drugs and Crime (UNODC) Early Warning Advisory (EWA) on New Psychoactive Substances6 have reported additional novel substances with an aminoindane structure, such as NM-2AI (N-methyl-2-aminoindane), 1-AI (1-aminoindane), and a fenfluramine analog ETAI (N-ethyl-5-trifluoromethyl-2-aminoindane); however, there is currently no scientific information available about these compounds.
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Aminoindans (AI) were originally studied as semi-rigid congeners of phenylethylamines, which are psychoactive alkaloids. 5-IAI is a psychoactive analog of p-iodoamphetamine and is indistinguishable, in its physiological effects, from 3,4-methylenedioxymethamphetamine in rats. A single 40 mg/kg dose of 5-IAI significantly reduces both serotonin uptake sites and hippocampal serotonin levels in rats. This product is intended for forensic applications.
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MDAI is an indane analog of 3,4-(methylenedioxy)amphetamine (MDA). In animal studies, MDAI effects are indistinguishable from 3,4-(methylenedioxy)methamphetamine (MDMA). While non-neurotoxic in animals when administered alone, MDAI produces significant serotonin neurotoxicity when given with dopaminergic agents.

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2-aminoindane also known as 2-indanylamine or 2-indanamine is an analog of the amphetamine family.

Like any other research chemical, 2AI can be insufflated, taken orally, injected or taken in by intravenous methods. Insufflation has been known to sting the nostrils though, with stinging effects lasting for quite a while. The oral method of dosage is by far the most acceptable for many individuals while the intravenous method is seen as the most dangerous or harmful, especially for individuals who are not skilled with the needle and syringe. Dosage may range from about 10-20mg for beginners to as high as 300mg for strong users, although this depends entirely on the individual concerned.
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MDAI sold online at alphabetapharmacy.com has a full IUPAC name of 6,7-dihydro-5H-indeno[5,6-d]-1,3-dioxol-6-amine, monohydrochloride which belongs to a class of phenethylamine research chemicals.
MDAI  might have entactogen and stimulant properties.
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